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The Proteasome Inhibitor Marizomib Evokes Endoplasmic Reticulum Stress and Promotes Apoptosis in Human Glioblastoma Cells

Proteasomes play an important role in the physiology of cancer cells, and inhibition of their activity may be used as a promising therapeutic strategy against glioblastoma (GBM). Although certain proteasome inhibitors (PIs) have been approved for the treatment of other malignancies, they have limite...

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Principais autores: Magdalena Kusaczuk, Natalia Tyszka, Rafał Krętowski, Marzanna Cechowska-Pasko
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2024-08-01
coleção:Pharmaceuticals
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Acesso em linha:https://www.mdpi.com/1424-8247/17/8/1089
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