Intracellular cholesterol: new functions and therapeutic approaches in NSCLC EGFR-TKI resistance
Abstract Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) have markedly enhanced survival rates among patients with advanced non-small cell lung cancer (NSCLC) exhibiting EGFR mutations. However, acquired resistance diminishes their therapeutic efficacy over time. Recent inves...
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| Principais autores: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2025-07-01
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| coleção: | Lipids in Health and Disease |
| Assuntos: | |
| Acesso em linha: | https://doi.org/10.1186/s12944-025-02559-w |
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