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Structural Analysis of the Putative Succinyl-Diaminopimelic Acid Desuccinylase DapE from <i>Campylobacter jejuni</i>: Captopril-Mediated Structural Stabilization

DapE is a highly conserved bacterial enzyme that produces L,L-diaminopimelic acid in the <i>meso</i>-diaminopimelic acid and lysine synthesis pathway, which is essential for peptidoglycan formation in the cell wall. DapE has been recognized as a promising antibacterial drug target and can be inhibit...

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Bibliografiske detaljer
Principais autores: Si Yeon Ahn, Young-Bong You, Han Byeol Oh, Min-Ah Park, Sung-il Yoon
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-12-01
Serier:Current Issues in Molecular Biology
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Online adgang:https://www.mdpi.com/1467-3045/47/12/1035
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