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Analysis of (p)ppGpp metabolism and signaling using a dynamic luminescent reporter.

As rapidly growing bacteria begin to exhaust nutrients, their growth rate slows, ultimately leading to the non-replicative state of quiescence. Adaptation to nutrient limitation requires widespread metabolic remodeling that is in part mediated by the phosphorylated nucleotides guanosine tetra- and p...

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Autori principali: Molly Hydorn, Sathya Narayanan Nagarajan, Elizabeth Fones, Caroline S Harwood, Jonathan Dworkin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science (PLoS) 2025-08-01
Serie:PLoS Genetics
Accesso online:https://doi.org/10.1371/journal.pgen.1011691
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