Postmortem Brains from Subjects with Diabetes Mellitus Display Reduced GLUT4 Expression and Soma Area in Hippocampal Neurons: Potential Involvement of Inflammation

Diabetes mellitus (DM) is an important risk factor for dementia, which is a common neurodegenerative disorder. DM is known to activate inflammation, oxidative stress, and advanced glycation end products (AGEs) generation, all capable of inducing neuronal dysfunctions, thus participating in the neuro...

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Detalhes bibliográficos

Principais autores:	Caio Yogi Yonamine, Marisa Passarelli, Claudia Kimie Suemoto, Carlos Augusto Pasqualucci, Wilson Jacob-Filho, Venâncio Avancini Ferreira Alves, Suely Kazue Nagahashi Marie, Maria Lucia Correa-Giannella, Luiz Roberto Britto, Ubiratan Fabres Machado
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-04-01
Colecção:	Cells
Assuntos:	GLUT4 diabetes obesity human hippocampus SH-SY5Y cell neurodegeneration
Acesso em linha:	https://www.mdpi.com/2073-4409/12/9/1250
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