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Transgenic Overexpression of the Proprotein Convertase Furin Enhances Skin Tumor Growth

Furin, one of the members of the family of proprotein convertases (PCs), ubiquitously expressed as a type I membrane-bound proteinase, activates several proteins that contribute to tumor progression. In vitro studies using cancer cell lines and clinical specimens demonstrated that furin processes im...

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書誌詳細
主要な著者: Jian Fu, Daniel E. Bassi, Jirong Zhang, Tianyu Li, Emmanuelle Nicolas, Andres J.P. Klein-Szanto
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2012-04-01
シリーズ:Neoplasia: An International Journal for Oncology Research
オンライン・アクセス:http://www.sciencedirect.com/science/article/pii/S1476558612800650
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