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Phosphorylation of AHR by PLK1 promotes metastasis of LUAD via DIO2-TH signaling.

Metastasis of lung adenocarcinoma (LUAD) is a major cause of death in patients. Aryl hydrocarbon receptor (AHR), an important transcription factor, is involved in the initiation and progression of lung cancer. Polo-like kinase 1 (PLK1), a serine/threonine kinase, acts as an oncogene promoting the ma...

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Principais autores: Chaohao Li, Derek B Allison, Daheng He, Fengyi Mao, Xinyi Wang, Piotr Rychahou, Ibrahim A Imam, Yifan Kong, Qiongsi Zhang, Yanquan Zhang, Jinghui Liu, Ruixin Wang, Xiongjian Rao, Sai Wu, B Mark Evers, Qing Shao, Chi Wang, Zhiguo Li, Xiaoqi Liu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2023-11-01
coleção:PLoS Genetics
Acesso em linha:https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1011017&type=printable
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