Immunoinformatics Analysis of SARS-CoV-2 ORF1ab Polyproteins to Identify Promiscuous and Highly Conserved T-Cell Epitopes to Formulate Vaccine for Indonesia and the World Population

SARS-CoV-2 and its variants caused the COVID-19 pandemic. Vaccines that target conserved regions of SARS-CoV-2 and stimulate protective T-cell responses are important for reducing symptoms and limiting the infection. Seven cytotoxic (CTL) and five helper T-cells (HTL) epitopes from ORF1ab were ident...

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Auteurs principaux:	Marsia Gustiananda, Bobby Prabowo Sulistyo, David Agustriawan, Sita Andarini
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2021-12-01
Collection:	Vaccines
Sujets:	SARS-CoV-2 immunoinformatics T-cell epitopes multi-epitope peptide-based vaccine cytotoxic T-cells helper T-cells
Accès en ligne:	https://www.mdpi.com/2076-393X/9/12/1459
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