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Complement C3 deficiency attenuates chronic hypoxia-induced pulmonary hypertension in mice.

Evidence suggests a role of both innate and adaptive immunity in the development of pulmonary arterial hypertension. The complement system is a key sentry of the innate immune system and bridges innate and adaptive immunity. To date there are no studies addressing a role for the complement system in...

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Detalhes bibliográficos
Principais autores: Eileen M Bauer, Han Zheng, Suzy Comhair, Serpil Erzurum, Timothy R Billiar, Philip M Bauer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2011-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3237464?pdf=render
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