Dereplication of Natural Product Antifungals via Liquid Chromatography–Tandem Mass Spectrometry and Chemical Genomics

Recently expanded reports of multidrug-resistant fungal infections underscore the need to develop new and more efficient methods for antifungal drug discovery. A ubiquitous problem in natural product drug discovery campaigns is the rediscovery of known compounds or their relatives; accordingly, we h...

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Detalhes bibliográficos

Principais autores:	Nathaniel J. Brittin, David J. Aceti, Doug R. Braun, Josephine M. Anderson, Spencer S. Ericksen, Scott R. Rajski, Cameron R. Currie, David R. Andes, Tim S. Bugni
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2024-12-01
coleção:	Molecules
Assuntos:	antifungal natural products mechanism of action dereplication chemical genomics metabolomics
Acesso em linha:	https://www.mdpi.com/1420-3049/30/1/77
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