IRAG1 Deficient Mice Develop PKG1β Dependent Pulmonary Hypertension
PKGs are serine/threonine kinases. PKG1 has two isoforms—PKG1α and β. Inositol trisphosphate receptor (IP<sub>3</sub>R)-associated cGMP-kinase substrate 1 (IRAG1) is a substrate for PKG1β. IRAG1 is also known to further interact with IP<sub>3</sub>RI, which mediates intracellular Ca<sup>2+</sup> rel...
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| Hauptverfasser: | , , , , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2020-10-01
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| Schriftenreihe: | Cells |
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| Online-Zugang: | https://www.mdpi.com/2073-4409/9/10/2280 |
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