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New sulfonamides containing organometallic-acylhydrazones: synthesis, characterisation and biological evaluation as inhibitors of human carbonic anhydrases

A series of organometallic acylhydrazones was prepared, incorporating Re(CO)3, Mn(CO)3 and ferrocenyl moieties, which were subsequently reacted with amino-sulfonamides in order to obtain carbonic anhydrase (CA, EC 4.2.1.1) inhibitors possessing organometallic moieties in their molecules. The new der...

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Principais autores: Yosselin Huentupil, Luis Peña, Néstor Novoa, Emanuela Berrino, Rodrigo Arancibia, Claudiu T. Supuran
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis Group 2019-01-01
Serija:Journal of Enzyme Inhibition and Medicinal Chemistry
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Online dostop:http://dx.doi.org/10.1080/14756366.2018.1555156
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