Structural and Functional Regulation of RyR2 in Cardiac Calcium Handling and Arrhythmogenesis
Cardiac Ca<sup>2+</sup> handling is critical for excitation–contraction coupling (ECC), with the ryanodine receptor type 2 (RyR2) serving as the key sarcoplasmic reticulum (SR) Ca<sup>2+</sup> release channel in cardiomyocytes. The dysfunction of RyR2 is linked to fatal cardiac arrhythmias, includin...
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| Principais autores: | , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI AG
2026-03-01
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| coleção: | Biomedicines |
| Assuntos: | |
| Acesso em linha: | https://www.mdpi.com/2227-9059/14/3/662 |
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