Emergence of blaKPC-71 variant and loss of aerobactin-encoding genes (iucABCD-iutA) in ST11-K64 carbapenem-resistant Klebsiella pneumoniae during ceftazidime–avibactam treatment

Objective: To investigate the within-host evolutionary dynamics of resistance and virulence in carbapenem-resistant Klebsiella pneumoniae during ceftazidime-avibactam treatment. Methods: Three K. pneumoniae strains were isolated from the sputum of the same patient. Broth microdilution method, whole-...

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Κύριοι συγγραφείς:	Fang-ling Du, Dan-dan Wei, Yong-qing Guo, Peng Liu, Yan-fang Mei, Shan-shan Huang, Qi-sen Huang, Lin-Ping Fan, Yang Liu
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Elsevier 2026-01-01
Σειρά:	Journal of Global Antimicrobial Resistance
Θέματα:	ST11-K64 CZA resistance blaKPC-71 Aerobactin iucABCD-iutA
Διαθέσιμο Online:	http://www.sciencedirect.com/science/article/pii/S2213716525002620
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