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Thioredoxin: a key factor in cold tumor formation and a promising biomarker for immunotherapy resistance in NSCLC

Abstract Immune checkpoint blockade (ICB) therapy has shown promising clinical efficacy in cancer treatment, but only a subset of patients experience significant therapeutic responses. Tumor cells respond to internal and external stresses, such as hypoxia and nutrient deprivation, by activating the...

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Principais autores: Jiayi Hu, Yilimunuer Abulimiti, Haiyang Wang, Dianyu Yang, Xu Wang, Yang Wang, Ping Ji
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2025-05-01
coleção:Respiratory Research
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Acesso em linha:https://doi.org/10.1186/s12931-025-03259-w
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