Neuron-selective changes in RNA transcripts related to energy metabolism in toxic models of parkinsonism in rodents
Dopamine (DA) neurons in the substantia nigra (SNDA neurons) are among the most severely affected in Parkinson's disease (PD). Mitochondrial complex I inhibition by rotenone or MPTP can induce SNDA neurodegeneration and recapitulate motor disability in rodents. We performed a transcriptional analysi...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2010-06-01
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| coleção: | Neurobiology of Disease |
| Assuntos: | |
| Acesso em linha: | http://www.sciencedirect.com/science/article/pii/S0969996110000756 |
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