The AXL-PYK2-PKCα axis as a nexus of stemness circuits in TNBC
A clinically relevant AXL-PYK2-PKCα axis where PYK2 and PKCα act as signaling nodes and functionally cooperate to converge stemness promoting pathways and regulate Oct4 and Nanog pluripotent TFs. Cancer stem cells (CSCs) are implicated in tumor initiation, metastasis and drug resistance, and conside...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Life Science Alliance LLC
2021-06-01
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| Schriftenreihe: | Life Science Alliance |
| Online-Zugang: | https://www.life-science-alliance.org/lookup/doi/10.26508/lsa.202000985 |
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