Design of fully synthetic signal peptide library and its use for enhanced secretory production of recombinant proteins in Corynebacterium glutamicum

Abstract Background Corynebacterium glutamicum is an attractive host for secretory production of recombinant proteins, including high-value industrial enzymes and therapeutic proteins. The choice of an appropriate signaling peptide is crucial for efficient protein secretion. However, due to the limi...

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Detalhes bibliográficos

Principais autores:	Eun Jung Jeon, Seong Min Lee, Hee Soo Hong, Ki Jun Jeong
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2024-09-01
Colecção:	Microbial Cell Factories
Assuntos:	Corynebacterium glutamicum Synthetic signal peptide Secretion Sec-dependent pathway Library screening
Acesso em linha:	https://doi.org/10.1186/s12934-024-02516-9
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