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Characterization and Management of Cytokine Release Syndrome From the MonumenTAL‐1 Study of Talquetamab in Patients With Relapsed/Refractory Multiple Myeloma

ABSTRACT Introduction Cytokine release syndrome (CRS) is a common adverse event associated with T‐cell redirection therapies (TCRT), including talquetamab, the first GPRC5D × CD3 bispecific antibody approved for relapsed/refractory multiple myeloma (RRMM). We describe CRS with talquetamab and implic...

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Principais autores: Niels W. C. J. van deDonk, Ajai Chari, Thomas Martin, Amrita Krishnan, Leo Rasche, Jing Christine Ye, Rakesh Popat, Brea Lipe, Cesar Rodriguez, Carolina Schinke, Sheri Skerget, Deeksha Vishwamitra, Raluca Verona, Jue Gong, Indrajeet Singh, Michela Campagna, Tara Masterson, Brandi Hilder, Jaszianne Tolbert, Thomas Renaud, M. Damiette Smit, Christoph Heuck, Maria‐Victoria Mateos
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-10-01
coleção:Cancer Medicine
Assuntos:
clinical management
cytokine release syndrome
GPRC5D
interleukin‐6
talquetamab
tocilizumab
Acesso em linha:https://doi.org/10.1002/cam4.71276
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