Metabolic vulnerability index and MetaboHealth score as risk factors for age-related macular degeneration in a large-scale prospective cohort

Abstract Background Age-related macular degeneration (AMD) imposes a substantial burden of disability. Metabolic disturbances are associated with increased AMD risk. Here we evaluate the metabolic vulnerability index (MVX), derived from inflammation- and malnutrition-related markers, and MetaboHealt...

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Principais autores:	Jun Yu, Yuzhou Zhang, Yue Lan Gao, Jian Ming Xu, Haoyu Chen, Mary Ho, Ka Wai Kam, Alvin L. Young, Chi Pui Pang, Clement C. Tham, Jason C. Yam, Li Jia Chen
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2026-02-01
Series:	Journal of Translational Medicine
Assuntos:	Age-related macular degeneration Metabolomics Polygenic risk score Retinal imaging
Acceso en liña:	https://doi.org/10.1186/s12967-026-07863-2
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