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Unraveling the Role of Heme in Neurodegeneration

Heme (iron-protoporphyrin IX) is an essential co-factor involved in several biological processes, including neuronal survival and differentiation. Nevertheless, an excess of free-heme promotes oxidative stress and lipid peroxidation, thus leading to cell death. The toxic properties of heme in the br...

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Bibliografiset tiedot
Päätekijät: Deborah Chiabrando, Veronica Fiorito, Sara Petrillo, Emanuela Tolosano
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2018-10-01
Sarja:Frontiers in Neuroscience
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Linkit:https://www.frontiersin.org/article/10.3389/fnins.2018.00712/full
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