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Intraventricular meningiomas frequently harbor NF2 mutations but lack common genetic alterations in TRAF7, AKT1, SMO, KLF4, PIK3CA, and TERT

Abstract Intraventricular meningiomas (IVMs) account for less than 5% of all intracranial meningiomas; hence their molecular phenotype remains unknown. In this study, we were interested whether genetic alterations in IVMs differ from meningiomas in other locations and analyzed our institutional seri...

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Principais autores: Gerhard Jungwirth, Rolf Warta, Christopher Beynon, Felix Sahm, Andreas von Deimling, Andreas Unterberg, Christel Herold-Mende, Christine Jungk
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2019-08-01
Serier:Acta Neuropathologica Communications
Fag:
Intraventricular meningioma
NF2
Targeted panel sequencing
SMARCB1
SMARCA4
Online adgang:http://link.springer.com/article/10.1186/s40478-019-0793-4
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