Two-Step Engineering of Food-Grade <i>Aspergillus oryzae</i> via Endogenous Signal Peptides and Vesicle Trafficking Proteins to Enhance Carrier-Free Protein Secretion

Heterologous protein secretion in filamentous fungi is often constrained by limitations in signal peptide recognition and intracellular trafficking. <i>Aspergillus oryzae</i>, a food-grade industrial fungus, has a robust native secretory system. However, its capacity for recombinant protein secretio...

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Detalhes bibliográficos

Principais autores:	Sarocha Panchanawaporn, Nakul Rattanaphan, Sukanya Jeennor, Jutamas Anantayanon, Weerapong Woraprayote, Laphaslada Pumpuang, Thipphiya Karirat, Nuttamon Prompakdee, Kobkul Laoteng, Chanikul Chutrakul
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2026-04-01
coleção:	Journal of Fungi
Assuntos:	<i>Aspergillus oryzae</i> secretory system protein secretion signal peptide Sec1/Munc18 protein vesicle trafficking
Acesso em linha:	https://www.mdpi.com/2309-608X/12/4/289
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