Daptomycin Resistant Staphylococcus aureus Clinical Strain With Novel Non-synonymous Mutations in the mprF and vraS Genes: A New Insight Into Daptomycin Resistance

Objectives: Daptomycin (DAP) resistance in Staphylococcus aureus is uncommon but there are increasing reports of the emergence of resistance during DAP therapy. Most clinical DAP-resistant S. aureus isolates investigated carried mutations in the mprF gene. The aim of this study was to identify mutat...

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Principais autores:	Artur J. Sabat, Marco Tinelli, Hajo Grundmann, Viktoria Akkerboom, Monica Monaco, Maria Del Grosso, Giulia Errico, Annalisa Pantosti, Alexander W. Friedrich
Formato:	Artigo
Idioma:	Inglês
Publicado:	Frontiers Media S.A. 2018-11-01
Series:	Frontiers in Microbiology
Assuntos:	whole-genome sequencing Staphylococcus aureus daptomycin SNP analysis MprF
Acceso en liña:	https://www.frontiersin.org/article/10.3389/fmicb.2018.02705/full
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