Investigation of binding behaviour of procainamide hydrochloride with human serum albumin using synchronous, 3D fluorescence and circular dichroism

Interaction of procainamide hydrochloride (PAH) with human serum albumin (HSA) is of great significance in understanding the pharmacokinetic and pharmacodynamic mechanisms of the drug. Multi-spectroscopic techniques were used to investigate the binding mode of PAH to HSA and results revealed the pre...

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Detalhes bibliográficos

Principais autores:	Kirthi Byadagi, Manjunath Meti, Sharanappa Nandibewoor, Shivamurti Chimatadar
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2017-04-01
Colecção:	Journal of Pharmaceutical Analysis
Assuntos:	Procainamide hydrochloride Human serum albumin Circular dichroism Synchronous fluorescence 3D fluorescence
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2095177916300612
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