Carbazole and tetrahydro-carboline derivatives as dopamine D3 receptor antagonists with the multiple antipsychotic-like properties

Dopamine D3 receptor (D3R) is implicated in multiple psychotic symptoms. Increasing the D3R selectivity over dopamine D2 receptor (D2R) would facilitate the antipsychotic treatments. Herein, novel carbazole and tetrahydro-carboline derivatives were reported as D3R selective ligands. Through a struct...

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Ngā kaituhi matua:	Zhongtang Li, Fan Fang, Yiyan Li, Xuehui Lv, Ruqiu Zheng, Peili Jiao, Yuxi Wang, Guiwang Zhu, Zefang Jin, Xiangqing Xu, Yinli Qiu, Guisen Zhang, Zhongjun Li, Zhenming Liu, Liangren Zhang
Hōputu:	Artigo
Reo:	Inglês
I whakaputaina:	Elsevier 2023-11-01
Rangatū:	Acta Pharmaceutica Sinica B
Ngā marau:	Dopamine D3 receptor Carbazole derivatives Tetrahydro-carboline Bitopic ligand Antipsychotic
Urunga tuihono:	http://www.sciencedirect.com/science/article/pii/S2211383523002861
Ngā Tūtohu:	Tāpirihia he Tūtohu Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!