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miR-193b-3p suppresses lung cancer cell migration and invasion through PRNP targeting

Abstract Background Tumor metastasis is responsible for approximately 90% of mortality in lung cancer. Understanding the molecular mechanisms of lung cancer metastasis is crucial for developing new treatment strategies. Cellular prion protein (PrPc), encoded by PRNP gene, was previously found to enh...

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Hlavní autoři: Hsiang-Ling Ho, Shin-Chih Lin, Chao-Wei Chiang, Ching Lin, Che-Wei Liu, Yi-Chen Yeh, Mei-Yu Chen, Teh-Ying Chou
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-02-01
Edice:Journal of Biomedical Science
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On-line přístup:https://doi.org/10.1186/s12929-025-01121-1
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