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Epidemiological, clinical, and severity characterization of sickle cell disease in a population from the Brazilian Amazon

Objective/background: Sickle cell disease (SCD) is a chronic inflammatory condition caused by a point mutation in the HBB gene. Here we characterized the clinical presentation of SCD in a population from Amazonas State in northern Brazil, in order to evaluate whether the higher Amerindian ancestry o...

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Autores principales: Purim Cesar, Anamika Dhyani, Luiz Augusto Schwade, Pollyana Acordi, Cinthia Xerez Albuquerque, Rejane Nina, Erich V. De Paula, Nelson Fraiji
Formato: Artigo
Lenguaje:Inglês
Publicado: Wolters Kluwer Medknow Publications 2019-10-01
Colección:Hematology/Oncology and Stem Cell Therapy
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Acceso en línea:https://journals.lww.com/10.1016/j.hemonc.2019.04.002
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