Molecular mechanisms of lung injury from ultra high and conventional dose rate pulsed radiation based on 4D DIA proteomics study

Abstract To investigate the mechanism of ultra-high dose rate pulsed radiation in radiation-induced lung injury (RILI), providing an experimental and theoretical basis for the application of FLASH-RT (FLASH-radiotherapy) in radiotherapy. C57BL/6J mice were randomly divided into three groups: a sham...

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Hlavní autoři:	MengHua Li, LiHui Zhang, AnNing Gao, Jing Xu, XinYu Wang, XiaoMan Liu, DongFei Yan, DongFang Zou, Shuang Wu, Bin Sun, GuoFu Dong, ChangZhen Wang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-02-01
Edice:	Scientific Reports
Témata:	Radiation-induced lung injury Ultra-high dose rate FLASH radiotherapy Fibrosis FLASH effect
On-line přístup:	https://doi.org/10.1038/s41598-025-87247-6
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