Transgenic CD8αβ co-receptor rescues endogenous TCR function in TCR-transgenic virus-specific T cells
Background Genetically engineered virus-specific T cells (VSTs) are a platform for adoptive cell therapy after allogeneic hematopoietic stem cell transplantation. However, redirection to a tumor-associated antigen by the introduction of a transgenic T-cell receptor (TCR) reduces anti-viral activity,...
Guardado en:
| Autores principales: | , , , , |
|---|---|
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BMJ Publishing Group
2020-10-01
|
| Colección: | Journal for ImmunoTherapy of Cancer |
| Acceso en línea: | https://jitc.bmj.com/content/8/2/e001487.full |
| Etiquetas: |
Sin Etiquetas, Sea el primero en etiquetar este registro!
|