Regulation of pyruvate dehydrogenase complex related to lactate switch in CHO cells

Abstract The metabolism of Chinese hamster ovary (CHO) cell lines is typically characterized by high rates of aerobic glycolysis with increased lactate formation, known as the ”Warburg” effect. Although this metabolic state can switch to lactate consumption, the involved regulations of the central m...

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Principais autores:	Johannes Möller, Krathika Bhat, Lotta Guhl, Ralf Pörtner, Uwe Jandt, An‐Ping Zeng
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Maximum Academic Press 2021-03-01
סדרה:	Engineering in Life Sciences
נושאים:	dynamic enzyme regulation lactate switch PDC phosphorylation Warburg effect
גישה מקוונת:	https://doi.org/10.1002/elsc.202000037
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!