Parainfluenza Virus 5 Priming Followed by SIV/HIV Virus-Like-Particle Boosting Induces Potent and Durable Immune Responses in Nonhuman Primates

The search for a preventive vaccine against HIV infection remains an ongoing challenge, indicating the need for novel approaches. Parainfluenza virus 5 (PIV5) is a paramyxovirus replicating in the upper airways that is not associated with any animal or human pathology. In animal models, PIV5-vectore...

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Bibliografski detalji

Glavni autori:	Peng Xiao, Krista Dienger-Stambaugh, Xuemin Chen, Huiling Wei, Shannon Phan, Ashley C. Beavis, Karnail Singh, Nihar R. Deb Adhikary, Pooja Tiwari, Francois Villinger, Biao He, Paul Spearman
Format:	Artigo
Jezik:	Inglês
Izdano:	Frontiers Media S.A. 2021-02-01
Serija:	Frontiers in Immunology
Teme:	parainfluenza virus 5 (PIV5) human immunodeficiency virus (HIV) vaccine virus-like particles (VLP) rhesus macaques immune responses
Online pristup:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.623996/full
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