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Curcumin, demethoxycurcumin, and bisdemethoxycurcumin induced caspase-dependent and –independent apoptosis via Smad or Akt signaling pathways in HOS cells

Abstract Background Osteosarcoma is the most common primary malignant bone tumor in children and adolescents and has also been associated with a high degree of malignancy and enhanced metastatic capacity. Curcumin (CUR) is well known for its anti-osteosarcoma activity. However, both demethoxycurcumi...

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Autors principals: Cheng Huang, Hsu-Feng Lu, Yu-Hsuan Chen, Jui-Chieh Chen, Wen-Hsiang Chou, Hsiu-Chen Huang
Format: Artigo
Idioma:Inglês
Publicat: BMC 2020-03-01
Col·lecció:BMC Complementary Medicine and Therapies
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Accés en línia:http://link.springer.com/article/10.1186/s12906-020-2857-1
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