Short linear motif acquisition, exon formation and alternative splicing determine a pathway to diversity for NCoR-family co-repressors

Vertebrate NCoR-family co-repressors play central roles in the timing of embryo and stem cell differentiation by repressing the activity of a range of transcription factors. They interact with nuclear receptors using short linear motifs (SLiMs) termed co-repressor for nuclear receptor (CoRNR) boxes....

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Autori principali:	Stephen Short, Tessa Peterkin, Matthew Guille, Roger Patient, Colin Sharpe
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	The Royal Society 2015-01-01
Serie:	Open Biology
Soggetti:	co-repressor ncor family alternative splicing short linear motifs pathway to diversity isoforms
Accesso online:	https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.150063
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