Melatonin Shields the Brain: Counteracting Iron Oxide Nanoparticle–Driven BACE1 Activation and Mitophagic Stress in Rats

Iron oxide nanoparticles (IONPs) therapy offers potential applications in a biomedical field but high doses may lead to neurotoxicity. Melatonin (MLT), known for its neuroprotective role, besides its natural chelating activity. Thus, we investigated the role of melatonin as a potential therapy to mi...

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Autors principals:	Doaa Abd El-hamied, Dina El-Kossi, Noha Rashed, Aliaa Mosa, Omnia Ismail, Hala Hassanin, Sally Anwer
Format:	Artigo
Idioma:	Inglês
Publicat:	Assiut University, Faculty of Pharmacy 2026-05-01
Col·lecció:	Bulletin of Pharmaceutical Sciences. Assiut University
Matèries:	Iron oxide nanoparticles Melatonin Oxidative stress BACE1 Neuropathological changes
Accés en línia:	https://bpsa.journals.ekb.eg/article_505571.html
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