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Gene expression profiling supports the hypothesis that human ovarian surface epithelia are multipotent and capable of serving as ovarian cancer initiating cells

<p>Abstract</p> <p>Background</p> <p>Accumulating evidence suggests that somatic stem cells undergo mutagenic transformation into cancer initiating cells. The serous subtype of ovarian adenocarcinoma in humans has been hypothesized to arise from at least two possible classes of progenitor cells: the...

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Principais autores: Matyunina Lilya V, Walker L DeEtte, Bowen Nathan J, Logani Sanjay, Totten Kimberly A, Benigno Benedict B, McDonald John F
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2009-12-01
Series:BMC Medical Genomics
Acceso en liña:http://www.biomedcentral.com/1755-8794/2/71
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