The occurrence of tarsal injuries in male mice of C57BL/6N substrains in multiple international mouse facilities.

Dislocation in hindlimb tarsals are being observed at a low, but persistent frequency in group-housed adult male mice from C57BL/6N substrains. Clinical signs included a sudden onset of mild to severe unilateral or bilateral tarsal abduction, swelling, abnormal hindlimb morphology and lameness. Cont...

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Principais autores:	Eleanor Herbert, Michelle Stewart, Marie Hutchison, Ann M Flenniken, Dawei Qu, Lauryl M J Nutter, Colin McKerlie, Liane Hobson, Brenda Kick, Bonnie Lyons, Jean-Paul Wiegand, Rosalinda Doty, Juan Antonio Aguilar-Pimentel, Martin Hrabe de Angelis, Mary Dickinson, John Seavitt, Jacqueline K White, Cheryl L Scudamore, Sara Wells
Formato:	Artigo
Idioma:	Inglês
Publicado:	Public Library of Science (PLoS) 2020-01-01
Series:	PLoS ONE
Acceso en liña:	https://doi.org/10.1371/journal.pone.0230162
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