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TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

Background Acquired somatic deletions and loss-of-function mutations in one or several codons of the TET2 (Ten-Eleven Translocation-2) gene were recently identified in hematopoietic cells from patients with myeloid malignancies, including myeloproliferative disorders and myelodys-plastic syndromes....

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Bibliografiske detaljer
Principais autores: Olivier Kosmider, Véronique Gelsi-Boyer, Marion Ciudad, Cindy Racoeur, Valérie Jooste, Norbert Vey, Bruno Quesnel, Pierre Fenaux, Jean-Noël Bastie, Odile Beyne-Rauzy, Aspasia Stamatoulas, François Dreyfus, Norbert Ifrah, Stéphane de Botton, William Vainchenker, Oliver A. Bernard, Daniel Birnbaum, Michaëla Fontenay, Eric Solary
Format: Artigo
Sprog:Inglês
Udgivet: Ferrata Storti Foundation 2009-12-01
Serier:Haematologica
Online adgang:https://haematologica.org/article/view/5432
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