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Tetra-gel enables superior accuracy in combined super-resolution imaging and expansion microscopy

Abstract The accuracy of expansion microscopy (ExM) depends on the structural preservation of samples embedded in a hydrogel. However, it has been unknown to what extent gel embedding alters the molecular positions of individual labeled sites. Here, we quantified the accuracy of gel embedding by usi...

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Autores principales: Hsuan Lee, Chih-Chieh Yu, Edward S. Boyden, Xiaowei Zhuang, Pallav Kosuri
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Portfolio 2021-08-01
Colección:Scientific Reports
Acceso en línea:https://doi.org/10.1038/s41598-021-96258-y
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