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The Iron Maiden. Cytosolic Aconitase/IRP1 Conformational Transition in the Regulation of Ferritin Translation and Iron Hemostasis

Maintaining iron homeostasis is fundamental for almost all living beings, and its deregulation correlates with severe and debilitating pathologies. The process is made more complicated by the omnipresence of iron and by its role as a fundamental component of a number of crucial metallo proteins. The...

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Uloženo v:
Hlavní autoři: Cécilia Hognon, Emmanuelle Bignon, Guillaume Harle, Nadège Touche, Stéphanie Grandemange, Antonio Monari
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2021-09-01
Edice:Biomolecules
Témata:
molecular dynamics
free energy profiles
iron homeostasis
aconitase
IRP
messenger RNA
On-line přístup:https://www.mdpi.com/2218-273X/11/9/1329
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