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Multi-omics identifies oxidative stress, prothrombotic pathways, and lactoperoxidase variants as key factors in COVID-19 severityResearch in context

Summary: Background: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected over 26 million individuals in Italy, resulting in ∼200,000 COVID-19-related deaths. Unravelling host genetic factors underlying disease severity is key to understanding progression mechanisms. Methods: We ap...

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Principais autores: Claudio Cappadona, Valeria Rimoldi, Francesca Tettamanzi, Giulia Cardamone, Alberto Mantovani, Giulia Soldà, Elvezia Maria Paraboschi, Rosanna Asselta
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2026-01-01
coleção:EBioMedicine
Assuntos:
COVID-19
Multi-omics
Oxidative stress
Lactoperoxidase
Thrombosis
Immune response
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2352396425005614
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