Sp1 facilitates continued HSV-1 gene expression in the absence of key viral transactivators

ABSTRACT Productive replication of herpes simplex virus (HSV) relies upon a well-ordered transcriptional cascade flowing from immediate-early (IE) to early (E) to late (L) gene products. While several virus-encoded transcriptional activators are involved in this process, IE and E gene promoters also...

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Autors principals:	Catherine N. Sodroski, Hyung Suk Oh, Shu-Fan Chou, David M. Knipe
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology 2024-03-01
Col·lecció:	mBio
Matèries:	herpes simplex virus transcription factor interferon transactivator ICP0 Sp1
Accés en línia:	https://journals.asm.org/doi/10.1128/mbio.03479-23
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