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Xiao-Shen-Formula, a Traditional Chinese Medicine, Improves Glomerular Hyper-Filtration in Diabetic Nephropathy via Inhibiting Arginase Activation and Heparanase Expression

Hyperglycemia induces glomerular hyper-filtration, which contributes to the development of diabetic nephropathy (DN), a condition that remains a challenge for treatment. The present study investigated the effect of Xiao-Shen-Formula (XSF) used for treatment of renal injury in type 1 DN mice model in...

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Principais autores: Xiaofei An, Maoxiang Zhang, Sisi Zhou, Tian Lu, Yongjun Chen, Lin Yao
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-09-01
Serier:Frontiers in Physiology
Fag:
diabetic nephropathy
glomerular hyper-filtration
Xiao-Shen-Formula
arginase
nitric oxide
heparanase
Online adgang:https://www.frontiersin.org/article/10.3389/fphys.2018.01195/full
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