Preliminary clinical study of p-iodo benzoyl moiety-modified PSMA inhibitors and prospective comparison with 68Ga-PSMA-11

Abstract Small-molecule inhibitors targeting prostate-specific membrane antigen (PSMA) have demonstrated promising results in the theranostics of prostate cancer (PCa). We designed and synthesized a novel small-molecule PSMA inhibitor, SC691. This study aimed to conduct a preliminary clinical prospe...

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Hlavní autoři:	Jianpeng Cao, Zhanliang Sun, Zhijun Zhou, Yilin Huang, Dengsai Peng, Xue Jiang, Yue Chen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-06-01
Edice:	Scientific Reports
Témata:	Prostate Cancer Prostate-Specific membrane antigen (PSMA) 68Ga-SC691 68Ga-PSMA-11 PET/CT
On-line přístup:	https://doi.org/10.1038/s41598-025-05344-y
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