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Diverse functions of homologous actin isoforms are defined by their nucleotide, rather than their amino acid sequence

β‐ and γ‐cytoplasmic actin are nearly indistinguishable in their amino acid sequence, but are encoded by different genes that play non‐redundant biological roles. The key determinants that drive their functional distinction are unknown. Here, we tested the hypothesis that β- and γ-actin functions ar...

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Autores principales: Pavan Vedula, Satoshi Kurosaka, Nicolae Adrian Leu, Yuri I Wolf, Svetlana A Shabalina, Junling Wang, Stephanie Sterling, Dawei W Dong, Anna Kashina
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications Ltd 2017-12-01
Colección:eLife
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Acceso en línea:https://elifesciences.org/articles/31661
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