Epigenetically elevated RAD51AP1 regulates the RAD51–UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma
Abstract. Background:. Epidermal growth factor receptor variant III (EGFRvIII) mutation is the most prevalent genetic change in glioblastoma. Abnormal DNA damage repair caused by EGFRvIII, which leads to temozolomide (TMZ) resistance, is a major cause of reduced postoperative survival in glioblasto...
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| Principais autores: | , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wolters Kluwer
2026-05-01
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| Serier: | Chinese Medical Journal |
| Online adgang: | http://journals.lww.com/10.1097/CM9.0000000000003567 |
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