Identifying prognostic markers in spatially heterogeneous breast cancer microenvironment

Abstract To gain deeper insights into the microenvironment of breast cancer, we utilized GeoMx Digital Spatial Profiling (DSP) technology to analyze transcripts from 107 regions of interest in 65 untreated breast cancer tissue samples. Our study revealed spatial heterogeneity in the expression of ma...

Полное описание

Библиографические подробности

Главные авторы:	Guohong Liu, Liping Wang, Lili Ji, Dan He, Lihua Zeng, Guangzheng Zhuo, Qian Zhang, Dujuan Wang, Yunbao Pan
Формат:	Artigo
Язык:	Inglês
Опубликовано:	BMC 2023-08-01
Серии:	Journal of Translational Medicine
Предметы:	Breast cancer Tumor microenvironment Immune infiltration Metabolic marker Immunological checkpoints Digital spatial profiling
Online-ссылка:	https://doi.org/10.1186/s12967-023-04395-x
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!