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Laeverin is Cell‐Surface Target for Liquid‐Phase Metastasizing Cancer Cells

Abstract Laeverin (LVRN) is a cell‐surface immunoregulatory factor that is specifically expressed in embryo‐derived extravillous trophoblast, which invades maternal spiral arteries without immune rejection during human placentation. Here, it is found that various epithelial cancer cell lines upregul...

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Principais autores: Haruki Kasama, Yuya Sakai, Kyosuke Kagami, Takashi Iizuka, Tatsuhito Kanda, Takuma Suzuki, Kayo Kayahashi, Masanori Ono, Tomoko Fujiwara, Shintaro Yagi, Noriyuki Inaki, Isao Matsumoto, Rena Yamazaki, Kaoru Abiko, Noriomi Matsumura, Akira Hattori, Takiko Daikoku, Hiroshi Fujiwara
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley 2025-12-01
coleção:Advanced Science
Assuntos:
antigen‐drug conjugate
cancer stem cell
distant metastasis
laeverin
liquid phase
Oct4
Acesso em linha:https://doi.org/10.1002/advs.202511349
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