Código QR (código de barras bidimensional)

Linderane Suppresses Hepatic Gluconeogenesis by Inhibiting the cAMP/PKA/CREB Pathway Through Indirect Activation of PDE 3 via ERK/STAT3

The role of phosphodiesterase 3 (PDE3), a cyclic AMP (cAMP)-degrading enzyme, in modulating gluconeogenesis remains unknown. Here, linderane, a natural compound, was found to inhibit gluconeogenesis by activating hepatic PDE3 in rat primary hepatocytes. The underlying molecular mechanism and its eff...

Fuld beskrivelse

Na minha lista:
Principais autores: Wei Xie, Yangliang Ye, Ying Feng, Tifei Xu, Suling Huang, Jianhua Shen, Ying Leng
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-05-01
Serier:Frontiers in Pharmacology
Fag:
cAMP
gluconeogenesis
linderane
phosphodiesterase
type 2 diabetes
Online adgang:http://journal.frontiersin.org/article/10.3389/fphar.2018.00476/full
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker