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Cyclosporine-insensitive mode of cell death after prolonged myocardial ischemia: Evidence for sarcolemmal permeabilization as the pivotal step.

A prominent theory of cell death in myocardial ischemia/reperfusion (I/R) posits that the primary and pivotal step of irreversible cell injury is the opening of the mitochondrial permeability transition (MPT) pore. However, the predominantly positive evidence of protection against infarct afforded b...

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Hlavní autoři: Katie J Sciuto, Steven W Deng, Paul W Venable, Mark Warren, Junco S Warren, Alexey V Zaitsev
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2018-01-01
Edice:PLoS ONE
On-line přístup:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0200301&type=printable
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